People » Ellen H. Kang

Kang
  • Assistant Professor
  • NSTC, PVL 427 (Office) and PVL 439 (Lab)
  • 407-823-2368
  • Ellen.Kang@ucf.edu

Dr. Kang received her B.S. and M.S. in Physics from Seoul National University, South Korea, and Ph.D. in Physics from Brown University. She did her postdoctoral training in Molecular Biophysics and Biochemistry at Yale University under the supervision of Professor Enrique De La Cruz. She joined UCF in Fall 2015 as an Assistant Professor.

  • Molecular biophysics and biomechanics of cytoskeletal protein self-assembly
  • Molecular mechanisms of actin-based mechano-transduction
  • Biopolymer and nanofiber mechanics

1. H. Li, T.-J. Ko, M. Lee, H.-S. Chung, S. S. Han, K. H. Oh, A. Sadmani, H. Kang and Y. Jung (2019) Experimental Realization of Few Layer 2D MoS2 Membranes of Near Atomic Thickness for High Efficiency Water Desalination. Nano Letters, DOI: https://doi.org/10.1021/acs.nanolett.9b01577

2. S. Ghanbari, A. M. Diaz, J. Park, H. Kang, and C. H. Niu. (2019) Equilibrium and heat of water vapor adsorption on the surface of natural lignocellulose materials. Chemical Engineering Research and Design, 147, 18-29

3. N. Castaneda, M. Lee, H. R. Jacquez, R. R. Marracino, T. R. Merlino, H. Kang* (2019) “Actin filament mechanics and structure in crowded environments.” J. Phys. Chem. B, DOI: 10.1021/acs.jpcb.8b12320 (Epub ahead of print)

4. M. Diaz, Z. Zhang, B. Lee, F. M. Hernandez Luna, Y. Y. Li Sip, X. Lu, J. Heidings, L. Tetard, L.Zhai*, and H. Kang*. (2018) “Evaluation of Single Hydrogel Nanofiber Mechanics Using Persistence Length Analysis”, ACS Omega, 3(12), 18304-18310

5. S. Ghosh, J. Park, M. Thomas, E. Cruz , O. Cardona, H. Kang, T. Jewett. (2018) “Biophysical characterization of actin bundles generated by the Chlamydia trachomatis Tarp effector.” Biochem. Biophys. Res. Commun., 500(2):423-428

6. N. Castaneda, T. Zheng, H. J. Rivera-Jacquez , H. J. Lee, J. Hyun, A. Balaeff, Q. Huo, H. Kang*. (2018) “Cations modulate actin bundle mechanics, assembly dynamics, and structure.” J. Phys. Chem. B, 122(14):3826-3835

7. W. A. Elam, W. Cao, H. Kang, A. Huehn, G. M. Hocky, E. Prochniewicz, A. C. Schramm, K. Negrón, J. Garcia, T. T. Bonello, P. W. Gunning, D. D. Thomas, G. A. Voth, C. V. Sindelar, E. M. De La Cruz. (2017) “Phosphomimetic S3D-cofilin binds but only weakly severs actin filaments.” J. Biol. Chem., 292(48):19565-19579

8. Z. A. O. Durer, R. M. McGillivary, H. Kang, W. A. Elam, C. L. Vizcarra, D. Hanein, E. M. De La Cruz, E. Reisler, M. E. Quinlan (2015), “Metavinculin tunes the flexibility and the architecture of vinculin induced bundles of actin filaments”, J. Mol. Biol., 427(17):2782-98.

9. H. Kang, M. J. Bradley, W. Cao, K. Zhou, E. E. Grintsevich, A. Michelot, C. V. Sindelar, M. Hochstrasser, and E. M. De La Cruz (2014) Site-specific cation release drives actin filament severing by vertebrate cofilin, Proc Natl Acad Sci U S A., 111(50): 17821-17826

10. J. S. Graham+, B. R. McCullough+, H. Kang, W. A. Elam, W. Cao, E. M. De La Cruz (2014) Multi-platform compatible software for analysis of polymer bending mechanics, PLoS One, 9(4):e94766

11. H. Kang+, M. J. Bradley+, W. A. Elam, E. M. De La Cruz (2013) Regulation of actin by ion-linked equilibria, Biophysical Journal, 105:2621-2628 (Invited review article, Featured cover art)

12. W. A. Elam, H. Kang, E. M. De La Cruz (2013) Competitive displacement of cofilin can promote actin filament severing, Biochem Biophys Res Commun., 438(4):728-731

13. W. A. Elam, H. Kang, E. M. De La Cruz (2013) Biophysics of actin filament severing by cofilin, FEBS Letters, 587(8):1215-9 (Invited review article)

14. H. Kang, M. J. Bradley, B. R. McCullough, A. Pierre, E. E. Grintsevich, E. Reisler and E. M. De La Cruz (2012) Identification of cation binding sites on actin that drive polymerization and modulate bending stiffness. Proc Natl Acad Sci U S A., 109(42): 16923-16927
15. R. McCullough, E. E. Grintsevich, C.K. Chen, H. Kang , A. L. Hutchison, A. Henn, W. Cao, C. Suarez, J. L. Martiel, L. Blanchoin, E. Reisler, E. M. De La Cruz (2011) Cofilin-linked changes in actin filament flexibility promote severing, Biophysical Journal, 101(1):151-9

16. Suarez, J. Roland, R. Boujemaa-Paterski, H. Kang, B.R. McCullough, A-C.Reymann, C. Guérin, J-L. Martiel, E.M. De La Cruz, L. Blanchoin (2011) Cofilin tunes the nucleotide state of actin filaments and severs at bare and decorated segment boundaries, Current Biology, 21(10):862-8 (Recommended article in Faculty of 1000 Cell Biology)

17. H. Kang, D. S. Perlmutter, V. B. Shenoy, J. X. Tang (2010) Observation and kinematic description of long actin tracks induced by spherical beads, Biophysical Journal, 99(9), 2793-2802 (Highlighted as a Featured Article)

18. H. Kang, J. Wang, S. J. Longley, J. X. Tang, S. K. Shaw (2010) Relative actin nucleation promotion efficiency by WASP and WAVE proteins in endothelial cells, Biochem Biophys Res Commun., 400, 661-666

19. H. Kang, A. E. Carlsson, J. X. Tang (2009) Kinetic overshoot in actin network assembly induced jointly by branching and capping proteins, Physical Review E, 80 (4), 041913

20. H. Kang, Q. Wen, P. A. Janmey, J. X. Tang, E. Conti, F. C. MacKintosh (2009) Non-linear elasticity of stiff filament networks: Strain-stiffening, negative normal stress, and filament alignment in fibrin gels, Journal of Physical Chemistry B, 113 (12), 3799-3805

21. J. X. Tang, H. Kang, J. Jia (2005) Intriguing self-assembly of large granules of F-actin facilitated by gelsolin and alpha-actinin, Langmuir, 21, 2789-2795